Disease: Gastrointestinal Stromal Tumors
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808
XIAP P98170 X-linked inhibitor of apoptosis Enzyme modulator 0.92 0.447 0.808
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
VIM P08670 vimentin 0.71 0.372 0.846
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846
VEGFC P49767 vascular endothelial growth factor C Signaling 0.50 0.459 0.769
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TEK Q02763 TEK receptor tyrosine kinase Kinase 1.00 0.462 0.692
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SHH Q15465 sonic hedgehog signaling molecule 0.98 0.461 0.846
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
PTPRC P08575 protein tyrosine phosphatase receptor type C Enzyme 1.00 0.435 0.808
PTPN1 P18031 protein tyrosine phosphatase non-receptor type 1 0.81 0.523 0.731
PTPA Q15257 protein phosphatase 2 phosphatase activator Enzyme modulator 0.99 0.480 0.846
PTK2B Q14289 protein tyrosine kinase 2 beta Kinase 0.94 0.448 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTCH1 Q13635 patched 1 1.00 0.398 0.885
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885